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Data source information

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Interactions available from major taxonomies

NCBI taxonomy identifier Scientific name Number of interactions
9606 Homo sapiens 462552
559292 Saccharomyces cerevisiae S288c 108979
7227 Drosophila melanogaster 60885
10090 Mus musculus 38566
40674 Mammalia 36345
4932 Saccharomyces cerevisiae 35561
3702 Arabidopsis thaliana 24946
6239 Caenorhabditis elegans 17843
83333 Escherichia coli K-12 16659
192222 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 11971
10116 Rattus norvegicus 11181
4896 Schizosaccharomyces pombe 9052
381518 Influenza A virus (A/Wilson-Smith/1933(H1N1)) 4087
632 Yersinia pestis 3956

Interactions available from major taxonomies (corrected)

NCBI taxonomy identifier Scientific name Number of interactions
9606 Homo sapiens 472494
559292 Saccharomyces cerevisiae S288c 122323
7227 Drosophila melanogaster 60888
10090 Mus musculus 35318
3702 Arabidopsis thaliana 24946
6239 Caenorhabditis elegans 17843
83333 Escherichia coli K-12 16450
192222 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 11971
10116 Rattus norvegicus 9679
284812 Schizosaccharomyces pombe 972h- 9387
381518 Influenza A virus (A/Wilson-Smith/1933(H1N1)) 4087
632 Yersinia pestis 3956
243276 Treponema pallidum subsp. pallidum str. Nichols 3642
1111708 Synechocystis sp. PCC 6803 substr. Kazusa 3232

Interactions

BHF_UCL BIND BIND_TRANSLATION BIOGRID CORUM DIP HPIDB HPRD I2D_IMEX INNATEDB INTACT INTCOMPLEX MATRIXDB MBINFO MOLCON MPACT MPIDB MPPI OPHID REACTOME SPIKE UNIPROTPP VIRUSHOST
BHF_UCL 518 14 16 53 7 40 28 3 10 508 3 1 1 11 53 40 24 2
BIND 62858 49843 20700 171 24290 5 1554 18 141 24309 166 3 8 7 5914 8 285 1683 701 601 449 169
BIND_TRANSLATION 60720 23763 167 25459 7 2284 23 195 25328 121 3 9 9 5857 7 291 2407 858 767 454 194
BIOGRID 324083 155 29717 6 9705 51 729 58547 175 13 20 74 4236 125 6833 5675 4452 1489 9406
CORUM 2607 155 1 154 9 26 362 67 1 2 4 15 239 159 95 51 21
DIP 74638 4 553 25 225 29461 220 5 7 12 6314 62 58 1278 979 393 549 286
HPIDB 725 3 722 3 5 1 5 5
HPRD 40536 18 404 5515 31 23 15 14 107 7243 2186 3253 203 2746
I2D_IMEX 434 10 433 5 2 6 58 40 29 4 2
INNATEDB 4932 658 11 3 2 4 19 639 466 255 52 53
INTACT 224568 446 74 329 211 6747 899 168 10253 2758 8344 5007 20720
INTCOMPLEX 968 1 113 7 7 75 77 20 60 7
MATRIXDB 324 2 32 51 7 1
MBINFO 330 2 1 28 15 11 3 5
MOLCON 212 3 21 24 6 2 2
MPACT 13398 232
MPIDB 954 2
MPPI 776 181 67 56 14 11
OPHID 47464 4504 6734 302 4313
REACTOME 141818 1231 247 423
SPIKE 27824 151 3157
UNIPROTPP 5049 46
VIRUSHOST 45538
(Exclusive to source) 10 11047 5247 235454 1921 28293 2 24695 3144 124654 416 192 1 1 5396 53 227 27290 131031 15652 28 22752

Interactors

BHF_UCL BIND BIND_TRANSLATION BIOGRID CORUM DIP HPIDB HPRD I2D_IMEX INNATEDB INTACT INTCOMPLEX MATRIXDB MBINFO MOLCON MPACT MPIDB MPPI OPHID REACTOME SPIKE UNIPROTPP VIRUSHOST
BHF_UCL 494 209 221 283 175 236 44 206 44 143 494 33 18 14 29 1 70 295 223 252 118 241
BIND 37441 29648 16135 1810 15796 260 2340 231 1209 19047 1334 80 111 125 4201 66 600 2702 1787 2321 2177 2303
BIND_TRANSLATION 36124 17308 1835 16294 281 2806 248 1362 19714 1253 88 120 132 3878 66 605 3075 2017 2591 2153 2528
BIOGRID 51873 2582 15512 420 6413 269 2307 32383 1604 121 131 180 4550 9 499 5880 3362 5484 3080 6001
CORUM 4363 1693 217 1542 216 1041 3780 318 59 82 146 2 408 2248 1616 1931 1063 1980
DIP 25804 241 1772 244 1305 20766 1442 77 104 135 4421 250 412 2541 1744 2145 2225 2252
HPIDB 782 309 44 227 782 25 22 19 27 1 1 60 492 280 416 184 591
HPRD 9841 188 1453 6115 238 97 55 119 7 264 5148 2890 4497 1009 4291
I2D_IMEX 448 171 448 46 17 14 56 2 87 298 217 251 160 254
INNATEDB 3619 3247 153 73 53 95 7 265 2169 1351 1823 674 1942
INTACT 73955 1982 191 273 275 4953 995 730 8287 4576 7192 4642 8991
INTCOMPLEX 2194 30 9 14 1039 37 65 319 332 265 550 266
MATRIXDB 231 7 7 1 17 142 130 113 37 106
MBINFO 273 17 2 1 39 92 74 71 53 81
MOLCON 275 52 191 148 165 115 181
MPACT 4995 1 894 3
MPIDB 995 1 11 8 10 19 10
MPPI 833 418 315 342 256 326
OPHID 9476 3908 6024 1448 6078
REACTOME 6013 3097 964 3112
SPIKE 8811 1286 5403
UNIPROTPP 4642 1419
VIRUSHOST 10283
(Exclusive to source) 6190 3607 14983 315 2555 1792 109 27173 115 19 24 18 407 773 905 905

Summary of mapping interaction records to RIGs (Table 5)

Source Total records Protein-related interactions PPI assigned to RIGID % Unique RIGIDs %
BHF_UCL 928 915 915 100.00 518 56.61
BIND 157736 91309 90816 99.46 62858 69.21
BIND_TRANSLATION 192923 84138 81773 97.19 60720 74.25
BIOGRID 790004 493818 491294 99.49 324083 65.97
CORUM 2844 2844 2844 100.00 2607 91.67
DIP 78781 77225 77052 99.78 74638 96.87
HPIDB 1458 1405 1405 100.00 725 51.60
HPRD 83022 83022 82983 99.95 40536 48.85
I2D_IMEX 892 891 891 100.00 434 48.71
INNATEDB 17496 17496 7111 40.64 4932 69.36
INTACT 344906 327730 327637 99.97 224568 68.54
INTCOMPLEX 1100 982 982 100.00 968 98.57
MATRIXDB 596 575 575 100.00 324 56.35
MBINFO 542 521 521 100.00 330 63.34
MOLCON 377 375 375 100.00 212 56.53
MPACT 16504 16504 16373 99.21 13398 81.83
MPIDB 1505 1504 1504 100.00 954 63.43
MPPI 1814 1758 1578 89.76 776 49.18
OPHID 73257 73257 73257 100.00 47464 64.79
REACTOME 141996 141996 141993 100.00 141818 99.88
SPIKE 29686 29686 28323 95.41 27824 98.24
UNIPROTPP 8952 8890 8890 100.00 5049 56.79
VIRUSHOST 45540 45540 45539 100.00 45538 100.00
(All) 1992859 1502381 1484631 98.82 797994 53.75

Assignment of protein interactors to ROGs (Table 3)

Source Protein interactors Assigned % Arbitrary Matching sequence New or obsolete sequence Unassigned Unique proteins
BHF_UCL 2060 2060 100.00 0 0 0 0 494
BIND 252251 251706 99.78 0 0 0 545 37441
BIND_TRANSLATION 257681 251597 97.64 40883 0 0 6084 36124
BIOGRID 53047 52116 98.24 11433 0 0 931 51873
CORUM 12916 12916 100.00 7 0 0 0 4363
DIP 26633 26551 99.69 2084 0 0 82 25804
HPIDB 3221 3221 100.00 0 0 0 0 782
HPRD 123812 123812 100.00 13563 95615 130 0 9841
I2D_IMEX 1932 1932 100.00 0 0 0 0 448
INNATEDB 40104 24918 62.13 0 0 0 15186 3619
INTACT 265428 265292 99.95 115 39 74 136 73955
INTCOMPLEX 3256 3256 100.00 0 0 0 0 2194
MATRIXDB 1171 1171 100.00 5 0 0 0 231
MBINFO 1134 1134 100.00 0 0 0 0 273
MOLCON 862 862 100.00 0 0 0 0 275
MPACT 40349 40199 99.63 0 0 0 150 4995
MPIDB 3238 3238 100.00 0 0 0 0 995
MPPI 3568 3361 94.20 16 0 0 207 833
OPHID 146514 146514 100.00 405 20 1014 0 9476
REACTOME 283992 283988 100.00 19 0 0 4 6013
SPIKE 65934 64561 97.92 967 0 0 1373 8811
UNIPROTPP 21185 21185 100.00 1 0 0 0 4642
VIRUSHOST 94874 94873 100.00 22 0 0 1 10283
(All) 1705162 1680463 98.55 69520 95674 1218 24699 122677

ROG summary

BHF_UCL BIND BIND_TRANSLATION BIOGRID CORUM DIP HPIDB HPRD I2D_IMEX INNATEDB INTACT INTCOMPLEX MATRIXDB MBINFO MOLCON MPACT MPIDB MPPI OPHID REACTOME SPIKE UNIPROTPP VIRUSHOST
P 2060 173353 33822 12875 3221 1932 24918 264204 3256 1166 1134 862 3238 283963 55189 21180 94851
P+IN 6
P+L 19764 746 2 22
P+N 64
P+X 3 2
PD 116272 2996 124085
PD+IN 2
PD+LQ 10197
PD+N 1014
PD+X 10
PD+XQ 26
PDIQ 732
PDQ 30573
PGD 613 2079 306
PGD+L 6300 10659 6 962
PGD+X 13
PI 418
PT 2084 2579 1 30579
PT+L 541 1
PTD 84164 1 44 114
PTD+LQ 4022
PTDIQ 13
PTDQ 2492
PTGD 17 1
PTGD+L 21 2
PTI 16
PTM 3
PU 16 34 396 6 8099 4
PU+L 17 7 76 5 19 5
PU+O 23
PU+X 610 2
PUD 7 143 17341
PUD+L 13 265
PUD+O 20
PUD+X 60 162 3526
PUT 4 15 2527
PUT+L 21 30 1
PUT+O 16
PUTD 4 9
PUTD+L 3 140
PV 7
PV+L 1
S 146 831 12454 115 1
S+L 25 1560 634
S+N 2
S+O 275
S+X 263
SD 1338 4690 3119
SD+L 215 327
SD+N 130
SD+O 11114
SD+X 1173
SGD 680
SGD+L 2124
SGD+O 15462
SI 45114
ST 4557 112 7093
ST+L 243 3767
ST+O 852
STD 18 702 8455
STD+L 5 645
STD+O 28208
STGD 2023
STGD+L 6026
STGD+O 39571
STI 6075
SU 32
SUD 47
SUD+L 33 25
SUD+O 2
SUD+X 568
SUTD 13
SUTD+L 28 15
SUTD+O 131